'Effects of specific collagen peptide supplementation combined with resistance training on Achilles tendon properties'

Found that consuming gelatin with vitamin C prior to exercise increased markers associated with collagen synthesis, suggesting a potential interaction between nutrition and connective tissue response to loading.

This study suggests that taking collagen-derived products with vitamin C 60 minutes before training can improve connective tissue repair, injury prevention, and tendon/ligament strength

'Improvement of activity-related knee joint discomfort following supplementation of specific collagen peptides'

Observed improvements in joint-related outcomes in physically active individuals supplementing with collagen peptides over time, within a structured daily intake. The study on physically active individuals demonstrated that the daily intake of collagen peptides led to a statistically significant reduction in activity-related knee joint pain after a 12 week treatment compared with placebo.

Overall, the study confirmed the efficacy of collagen peptide intake on activity-related knee joint discomfort making it a potentially interesting option for the treatment of joint pain induced by physical stress.

'Vitamin C-enriched gelatin supplementation before intermittent activity augments collagen synthesis'

Reported that 14 weeks of daily specific collagen peptide (SCP) supplementation, combined with high-load resistance training, led to significantly greater improvements in Achilles tendon and patellar tendon cross-sectional area (CSA) and hypertrophy compared to resistance training alone in healthy men.

The study indicates that, along with enhanced tendinous adaptations, the supplementation also increased muscle thickness more than training alone, potentially reducing tendon stress and lowering the risk of injuries during training

'The effects of collagen peptides on muscle damage, inflammation and bone turnover following exercise: a randomized, controlled trial'

Found that consuming daily collagen peptides significantly reduces muscle soreness and aids in recovery (e.g., faster Countermovement Jump recovery) up to 48 hours after strenuous exercise.

The study suggests collagen helps manage exercise-induced muscle damage (EIMD) and improves recovery.

'Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: A randomised controlled trial'

Found that 15g of daily collagen peptites supplementation with 12 weeks of resistance training significantly improved body composition in elderly sarcopenic men compared to a placebo. Participants showed higher increases in fat-free mass (4.2 kg vs. 2.9 kg), improved isokinetic strength, and greater fat loss.

The study concluded that collagen peptides are an effective nutritional strategy to enhance the benefits of resistance training in older adults.

'Effects of 12 Weeks of Hypertrophy Resistance Exercise Training Combined with Collagen Peptide Supplementation on the Skeletal Muscle Proteome in Recreationally Active Men.'

Observed that the combination of specific collagen peptide (CP) supplementation and hypertrophy resistance training (RET) over a 12-week periodresulted in significant improvements in body composition and strength in recreationally active young men compared to a placebo group.

The study concluded that daily intake of 15g of collagen peptides, when combined with intensive resistance training, is superior to training alone for improving body composition.

'Specific Collagen Peptides in Combination with Resistance Training Improve Body Composition and Regional Muscle Strength in Premenopausal Women: A Randomized Controlled Trial'

Studied daily supplementation with 15g of specific collagen peptides alongside a 12-week resistance training program led to a significantly higher increase in fat-free mass and a greater decrease in fat mass compared to a placebo group.

Demonstrated that supplementing with 15g of collagen peptides daily while performing resistance training significantly increases fat-free mass and hand-grip strength while decreasing fat mass in premenopausal women more effectively than training alone.

'Impact of collagen peptide supplementation together with long-term resistance training on maximal strength and muscle size in healthy adults – A systematic review and meta-analysis'

Examined the effects of specific bioactive collagen peptides (BCP) on joint discomfort, with studies demonstrating that a daily, consistent dosage is key to achieving beneficial results.

The intervention protocols demonstrated that consistent supplementation (~15g/day) leads to significant improvements in collagen synthesis and connective tissue health, rather than sporadic use and that sustained, daily intake of specific collagen peptides is effective for enhancing tissue repair, such as in bone mineral density and tendon remodeling.

'Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis'

Found that the 15g dose (supplemented with Vitamin C) was relevant because it was found to double the marker of collagen synthesis in the blood, whereas a lower dose of 5g was not significantly better than a placebo

The study specifically tested 0g, 5g, and 15g doses of collagen supplementation. While all doses increased amino acids, the 15g dose significantly increased circulating proline, hydroxyproline, and hydroxylysine (the key building blocks of collagen), peaking at 1 hour post-consumption.

'Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis'

found that consuming 15 g of vitamin C-enriched gelatin or hydrolyzed collagen approximately one hour before exercise can improve collagen synthesis in recreationally active individuals.

The researchers concluded that taking vitamin C-enriched collagen or gelatin 1 hour before exercisem ay be a viable nutritional strategy to support musculoskeletal health and injury prevention by augmenting the body's natural collagen-building response to mechanical loading.

'Effect of collagen supplementation on osteoarthritis symptoms: a meta-analysis of randomized placebo-controlled trials'

found that oral collagen supplementation significantly reduces symptoms of osteoarthritis, specifically improving joint function and reducing pain as measured by the WOMAC and VAS scales.

While this specific meta-analysis focused on the efficacy of collagen for osteoarthirits, the broader scientific context often links collagen metabolism to essential co-factors such as Vitamin C

'Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis'

Vitamin C-enriched gelatin supplementation, when consumed one hour before short bouts of intermittent activity,significantly increases collagen synthesis.

Research demonstrates that this nutritional strategy can double the markers of collagen synthesis compared to exercise alone, potentially aiding in injury prevention and tissue repair.

'Vitamin C–enriched gelatin supplementation before intermittent activity augments collagen synthesis'

Demonstrated increased markers of collagen synthesis when gelatin was consumed with vitamin C prior to exercise, highlighting the interaction between intake timing and mechanical loading.

'Effects of Different Vitamin C-Enriched Collagen Derivatives on Collagen Synthesis'

Conducted research highlighting that consuming 15g of vitamin C-enriched collagen (either gelatin or hydrolyzed collagen) approximately 60 minutes before exercise (such as jump rope or resistance training) significantly improves collagen synthesis in connective tissue.

Their work demonstrated that this timing maximizes the delivery of collagen-specific amino acids (glycine, proline, and hydroxyproline) to the tissues during the elevated blood flow triggered by the exercise.

'Oral Supplementation of Specific Collagen Peptides Combined with Calf-Strengthening Exercises Enhances Function and Reduces Pain in Achilles Tendinopathy Patients'

The supplement is ingested ~30-60 minutes pre-exercise, allowing for peak amino acid availability in the blood during the heightened collagen synthesis induced by mechanical loading of the tendon.

The Study found that about 15–30 min after oral ingestion of collagen hydrolysates, free and peptide forms of serum hydroxyproline levels significantly increase and reach a maximum after 30–60 min.